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Prostate & Testicular Cancer Screening Tests: PSA, AFP & hCG
Track PSA, AFP, hCG, and LDH, the key tumor markers for prostate and testicular health, with lab tests you can order online.
Affiliate disclosure: we earn a commission when you purchase lab tests through links on this site, at no extra cost to you. Learn more
Single tumor-marker tests from $15.96 and PSA testing from $23.16 with promotional pricing; multi-marker men's panels range from $46.36 up to $899.16 (pricing at time of writing).
At a glance
Prostate and testicular screening blood tests measure tumor markers, including total and free PSA, AFP, hCG, and LDH, that are associated with prostate and testicular conditions. These direct-to-consumer options range from a single PSA test to multi-marker men's cancer screening panels, and are designed for men who want a baseline or an ongoing view of these markers. Results are delivered confidentially and are meant to be reviewed with your doctor.
Best suited for
- Men over 50, or younger men with a family history of prostate concerns, who want to establish a PSA baseline
- Men noticing urinary changes, increased frequency, urgency, or a weak stream, who plan to see a doctor and want lab data in hand
- Men who have noticed a testicular lump, swelling, or heaviness and are working with a clinician on next steps
- Men already tracking PSA or tumor-marker trends between physician visits
- Men who want a combined view of prostate markers and total testosterone from one blood draw
What's included
PSA Total Test
PSA Free and Total Test
PSA Total and Testosterone, Total, Males
Proactive Cancer Screening: Essential Prostate & Testicular Health Panel
CA-1. Cancer Screening - Men
CA-2. Cancer Screening - Men
CA-3. Cancer Screening - Men
CA-4. Cancer Screening - Men
Cancer Blood Tests: 18 Key Lab Tests Used in Cancer Screening
AFP Test
Alpha-Fetoprotein and AFP-L3 Test
Lactate Dehydrogenase Test
hCG Total Quantitative Test
hCG Qualitative Urine Test
Cancer Tumor Markers (Men) - Basic
Cancer Tumor Markers (Men) - Basic Plus
Cancer Tumor Markers (Men) - Comprehensive
Deep-dive the key markers: Total Testosterone
Key biomarker ranges
Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.
Adult male ranges shown; commonly used reference ranges run roughly 300–1,000 ng/dL, with morning draws the standard since levels peak early in the day.
| Zone | Range |
|---|---|
| Low | 0–300 ng/dL |
| Normal range | 300–1000 ng/dL |
| High | 1000–1200 ng/dL |
The importance of testing
PSA (prostate-specific antigen) is the most widely used blood marker for prostate health. An elevated total PSA is associated with prostate cancer, but also with non-cancerous conditions such as benign prostatic hyperplasia (BPH) and prostatitis. That is why the free and total PSA option matters: reporting the unbound fraction alongside total PSA gives your doctor additional context when interpreting an elevated result, and a combined PSA plus total testosterone panel adds a hormonal dimension to the same blood draw.
For testicular health, the markers are different. AFP (alpha-fetoprotein), hCG (human chorionic gonadotropin), and LDH (lactate dehydrogenase) are the tumor markers clinicians most often use when evaluating testicular concerns. Each is available here as an individual test, and all three appear inside the larger men's cancer screening panels, which bundle tumor markers with broader health biomarkers.
With tumor markers, the trend is usually more informative than any single number. Establishing a baseline while you feel well, then retesting on a schedule you set with your physician, makes a rising or falling pattern visible early, which is exactly how doctors use these markers to track prostate health over time or monitor a known condition.
If you are noticing symptoms, changes in urination such as urgency, frequency, or a weak stream; pelvic, testicular, or lower back discomfort; or a new lump, swelling, or heaviness in a testicle, lab results are a useful data point to bring to that appointment, but they are not a substitute for seeing a healthcare provider. Screening results flag findings to review with your doctor; they are not intended to confirm any condition on their own.
Promo code
ULTA2E51Save 20% with code ULTA2E51, current promotion; confirm final pricing on the partner page.
Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.
Order NowFrequently asked questions
What does the PSA test measure?
The PSA test measures prostate-specific antigen, a protein made by the prostate gland, in a blood sample. Elevated PSA is associated with prostate cancer as well as non-cancerous conditions such as benign prostatic hyperplasia (BPH) and prostatitis, which is why results are best interpreted by your doctor alongside your age, history, and prior values.
What is the difference between a total PSA test and a free and total PSA test?
A total PSA test reports a single number, all PSA circulating in your blood, while a free and total PSA test also reports the unbound (free) fraction and the ratio between the two. Doctors often use the free-to-total ratio for added context when total PSA is elevated, since it can help distinguish patterns associated with benign prostate conditions from those associated with prostate cancer.
Which blood tests screen for markers associated with testicular cancer?
AFP (alpha-fetoprotein), hCG (human chorionic gonadotropin), and LDH (lactate dehydrogenase) are the tumor markers most commonly used in testicular evaluations, and each is available individually or within the multi-marker men's panels. Abnormal results do not confirm cancer on their own, they flag findings to review with your doctor, who may recommend an exam or imaging.
Can I order prostate and testicular screening tests without a doctor's visit?
Yes, these are direct-to-consumer lab tests you can order online, then complete with a quick blood draw at a partner lab near you. No referral is required to purchase, results are kept confidential and returned quickly, and we recommend sharing them with your physician, especially if anything is out of range.
Is direct-to-consumer lab testing available in every US state?
No, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout. In most other US states you can order online and visit a local lab for your sample collection.
Do these tests confirm prostate or testicular cancer?
No, these tests measure tumor markers associated with prostate and testicular conditions; they are not intended to confirm any disease on their own. Screening results are a starting point: your doctor interprets them in context and decides whether follow-up such as an exam, imaging, or repeat testing makes sense for you.
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