MetabolicMarkers

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Current promotion

Brain Health Blood Tests: Cognitive Function & Nutrient Panels

Objective biomarker data for focus, mental energy, and long-term cognitive health.

Affiliate disclosure: we earn a commission when you purchase lab tests through links on this site, at no extra cost to you. Learn more

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Panels from $179.96 to $907.16 with the 20% code (list prices $224.95–$1,133.95), promotional pricing at time of writing.

At a glance

Brain health blood test panels measure biomarkers associated with cognitive function, including inflammation markers like C-reactive protein (CRP), homocysteine, vitamin B12, folate, vitamin D, and heavy metals such as lead and mercury. They are designed for adults experiencing brain fog, low mental stamina, or focus issues, and for anyone taking a proactive, data-driven approach to long-term brain health. Results are meant to be tracked over time and reviewed with your doctor, not intended to confirm any condition.

Best suited for

  • Adults experiencing brain fog, low mental stamina, or trouble sustaining focus
  • Anyone taking a proactive, risk-aware approach to long-term cognitive health
  • Older adults who want to check vitamin B12, folate, and vitamin D status
  • People tracking inflammation, homocysteine, or insulin-resistance markers alongside heart health
  • Those noticing changes in thinking, memory, or alertness after starting a medication

What's included

Brain Optimization Panel

13 tests, 39 biomarkers (blood), a baseline view of brain-related markers for focus, mental energy, and proactive cognitive health

Brain Fit Comprehensive Panel

51 tests, 145 biomarkers, the broadest multi-system evaluation for complex or persistent symptoms

Neurotransmitter Panel

explores neurotransmitter-related patterns associated with mood, stress response, motivation, and attention

Neurotransmitters and Neurologic Health Panel

9 tests, 63 biomarkers, neurotransmitter insight plus additional neurologic-support markers

Medication Clarity & Brain Balance Panel

4 tests, 5 biomarkers, vitamin B12, methylmalonic acid (MMA), folate, homocysteine, and ammonia

Deep-dive the key markers: hs-CRP, Vitamin D, Fasting Insulin

Key biomarker ranges

Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.

hs-CRP (mg/L)

Commonly used cutoffs: under 1 mg/L low, 1–3 mg/L average, over 3 mg/L high; acute illness or injury can spike results, so retesting confirms a trend.

hs-CRP reference ranges (mg/L)
ZoneRange
Low01 mg/L
Average13 mg/L
High310 mg/L
Vitamin D (25-OH) (ng/mL)

Commonly used cutoffs: below 20 ng/mL deficient, 20–30 insufficient, 30–60 a frequently cited target band; season and supplementation move levels substantially.

Vitamin D (25-OH) reference ranges (ng/mL)
ZoneRange
Deficient020 ng/mL
Insufficient2030 ng/mL
Sufficient3060 ng/mL
High60100 ng/mL
Fasting Insulin (µIU/mL)

Commonly used reference ranges accept up to ~25 µIU/mL, but many clinicians view single-digit fasting insulin as the more informative target; assays vary by lab.

Fasting Insulin reference ranges (µIU/mL)
ZoneRange
Low02 µIU/mL
Optimal210 µIU/mL
Above optimal1025 µIU/mL
High2530 µIU/mL

The importance of testing

Cognitive performance is tightly connected to systems you can actually measure: inflammation, metabolic health, nutrient status, cardiovascular risk, and environmental exposures. Chronic inflammation, flagged by markers such as C-reactive protein (CRP), is increasingly associated with brain fog, fatigue, and long-term cognitive decline, testing gives you and your clinician a clearer picture of one possible contributor.

Heart and brain share risk factors. Homocysteine is a biomarker associated with stroke, heart disease, and dementia risk, and identifying elevated levels early supports timely conversations with your doctor about diet, B vitamins, and cardiovascular risk management. Insulin resistance, which often appears years before type 2 diabetes, is likewise associated with changes in cognitive health over time, spotting it early opens the door to preventive steps through nutrition, movement, and clinician-guided care.

Nutrient status matters too. Deficiencies in vitamin D, vitamin B12, and folate are common, especially in older adults, and may influence cognition, energy, and neurologic function. The broader panels also screen for heavy metals such as lead and mercury, environmental exposures that can affect neurologic health.

The practical value is in trends: establish a baseline, retest after changes to diet, supplements, or medications, and bring the numbers to your doctor. These panels measure and track markers, they are not intended to confirm any condition, so view results as the starting point for an informed conversation about next steps.

Promo code

BRAINOPT100

Save 20% with code BRAINOPT100, current promotion; confirm final pricing on the partner page.

Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.

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Frequently asked questions

What do brain health lab panels measure?

Brain health panels measure biomarkers associated with cognitive function, including inflammation markers like C-reactive protein (CRP), homocysteine, vitamin B12, folate, vitamin D, insulin-resistance markers, and, in the broader panels, heavy metals such as lead and mercury. Depending on the panel, a single order covers anywhere from 5 to 145 biomarkers across blood and, for some panels, urine samples.

Can these tests confirm dementia or Alzheimer's disease?

No, these panels are not intended to confirm any condition. They measure markers associated with inflammation, nutrient status, metabolic health, and cardiovascular risk that research links to long-term cognitive health. Out-of-range results are a flag to review with your doctor, who can decide whether further evaluation is appropriate.

Do I need a doctor's visit to order these tests?

No, you can order these panels online without a doctor's visit. You choose your panel, apply the promo code at checkout, complete your sample collection as directed (specimen type varies by panel), and then review your results, which you can share with your own clinician for next steps.

Which brain panel should I start with?

The Brain Optimization Panel is the most popular starting point, covering 13 tests and 39 biomarkers tied to focus, mental energy, and proactive cognitive health. Choose the Brain Fit Comprehensive Panel if your symptoms feel complex or multi-factor, a neurotransmitter panel if mood, motivation, or stress response is your main question, or the Medication Clarity & Brain Balance Panel if thinking changes started with a medication.

Can I order these lab tests in every US state?

No, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout. Availability can also vary by lab location, so confirm on the partner page before ordering.