MetabolicMarkers

Educational content only, not medical advice. We are not a medical provider; review your results with a licensed physician. Details

Current promotion

Liver Function Blood Tests: ALT, AST, GGT & Full Hepatic Panels

Track the enzymes, proteins, and clotting factors that reflect how well your liver is working.

Affiliate disclosure: we earn a commission when you purchase lab tests through links on this site, at no extra cost to you. Learn more

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Individual liver-related tests from $19.95 and bundled Liver Health panels from $69.95; the 20% promotion brings these to $15.96 and $55.96 (promotional pricing at time of writing).

At a glance

Liver function blood testing measures the enzymes, proteins, and clotting factors, including ALT, AST, ALP, GGT, bilirubin, and albumin, that reflect how well your liver is processing, filtering, and synthesizing what your body needs. These panels suit adults who want a clear baseline of liver-related markers, whether for routine wellness tracking or because a risk factor like alcohol use, excess weight, or long-term medication use applies to them. You can order online without a doctor's visit and review results with your own clinician.

Best suited for

  • Adults who want a baseline picture of liver enzymes and proteins as part of routine wellness tracking
  • People with risk factors such as regular alcohol use, excess weight, diabetes, or a family history of liver conditions
  • Anyone taking long-term medications or supplements whose clinician recommends periodic liver labs
  • Those noticing subtle changes, persistent fatigue, itchy skin, dark urine, who want lab data to review with a doctor
  • Self-trackers who prefer ordering their own labs and following trend reports over time

What's included

LH-1 Liver Health Panel

Focused baseline: GGT, Hepatic Function Panel, LDH, and PT with INR (4 tests, 14 biomarkers)

LH-2 Liver Health Panel

Adds alpha-1-antitrypsin, AFP with AFP-L3, fractionated bilirubin, ceruloplasmin, CMP, and iron studies (9 tests, 34 biomarkers)

LH-3 Liver Health Panel

Extends LH-2 with copper and hepatitis A, B, and C screening (14 tests, 41 biomarkers)

LH-4 Liver Health Panel

Most comprehensive option, spanning enzymes, proteins, genetic markers, and hepatitis screening (16 tests, 44 biomarkers)

Hepatic Function Panel (LFT)

Gamma-Glutamyl Transferase (GGT) Test

Lactate Dehydrogenase (LDH) Test

Prothrombin Time with INR Test

Comprehensive Metabolic Panel (CMP) Test

Iron and Total Iron Binding Capacity (TIBC) Test

Ceruloplasmin Test

Alpha-1 Antitrypsin Quantitative Test

Alpha-Fetoprotein and AFP-L3 Test

Deep-dive the key markers: ALT, eGFR, Fasting Glucose, Ferritin

Key biomarker ranges

Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.

ALT (U/L)

Commonly used cutoffs place ALT below roughly 30–40 U/L, with slightly lower thresholds often cited for women; recent exercise and alcohol can raise results.

ALT reference ranges (U/L)
ZoneRange
Optimal030 U/L
Borderline high3050 U/L
High50100 U/L
eGFR (mL/min/1.73m²)

For eGFR, lower is worse: 90+ is consistent with full kidney function, while sustained values below 60 are the commonly used threshold of concern.

eGFR reference ranges (mL/min/1.73m²)
ZoneRange
Kidney failure range015 mL/min/1.73m²
Reduced1560 mL/min/1.73m²
Mildly reduced6090 mL/min/1.73m²
Optimal90120 mL/min/1.73m²
Fasting Glucose (mg/dL)

Commonly used reference ranges place fasting glucose at 70–99 mg/dL; results vary with sleep, stress, and recent illness, and labs differ slightly.

Fasting Glucose reference ranges (mg/dL)
ZoneRange
Low5070 mg/dL
Optimal70100 mg/dL
Prediabetic range100126 mg/dL
Diabetic range126160 mg/dL

The importance of testing

Your liver quietly handles detoxification, digestion support, and protein production, and changes in liver-related markers often show up in blood work before anything is noticeable day to day. Core liver function tests track enzymes such as ALT and AST (markers associated with liver cell stress), ALP and GGT (markers associated with bile flow and with alcohol or medication effects), plus bilirubin, albumin, and total protein, which reflect how the liver processes waste and builds essential proteins.

Expanded panels add context around those core numbers. A comprehensive metabolic panel folds in electrolytes, glucose, and kidney values; iron and TIBC screen for markers associated with iron overload or deficiency; and specialty tests like ceruloplasmin, alpha-1 antitrypsin, and alpha-fetoprotein (AFP with AFP-L3) measure proteins associated with less common inherited and liver-specific conditions. Hepatitis A, B, and C screening is available in the broader panels for those with relevant exposure history.

The real value is in trends. Establishing a baseline and re-testing over time lets you and your doctor see whether markers are stable, improving, or drifting, useful when you are adjusting lifestyle habits, monitoring a long-term medication, or following up on a previous out-of-range result. Results arrive privately, often within 24–48 hours, in a portal with trend charts built for exactly this kind of tracking.

Promo code

LH20

Save 20% with code LH20, current promotion; confirm final pricing on the partner page.

Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.

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Frequently asked questions

What do liver function blood tests measure?

Liver function tests measure enzymes and proteins, ALT, AST, ALP, GGT, bilirubin, albumin, and total protein, along with PT/INR, which reflects the liver's production of clotting factors. Together these markers show how the liver is processing waste, supporting digestion, and synthesizing proteins, and they give your doctor concrete numbers to interpret alongside your history.

Can I order liver testing without a doctor's visit?

Yes, no doctor's visit is needed to place an order, because the partner lab provides the physician requisition. You order online, visit one of about 2,100 draw locations (most visits take 15–30 minutes), and results are delivered to a private portal, often within 24–48 hours, to review with your own clinician.

Do I need to fast before a liver panel?

Usually not, fasting is not typically required for standard liver function tests. If you add lipids or fasting glucose, plan on 8–12 hours of fasting, and avoid heavy alcohol and strenuous exercise for 24 hours before your draw unless your clinician advises otherwise.

Which liver panel should I start with?

A strong starting baseline covers ALT, AST, ALP, GGT, total and direct bilirubin, albumin, total protein, and PT/INR, the focused LH-1 panel or the standalone Hepatic Function Panel covers most of this ground. Broader panels layer in a comprehensive metabolic panel, iron studies, hepatitis screening, and specialty markers; your doctor can help match a panel to your risk profile.

Is this testing available in every US state?

No, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout. Most other US states are served through the partner's nationwide network of draw locations.

Can I pay with HSA or FSA funds?

Yes, HSA/FSA cards are accepted at checkout. Pricing is cash-pay and shown upfront, so there are no surprise insurance bills.