Current promotion
Hashimoto's Antibody Testing: TPO & Thyroglobulin Blood Tests
Antibody markers associated with autoimmune thyroid activity, measured alongside your core thyroid hormones.
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Hashimoto's-focused panels from $55.96 with the 20% promotion applied (pricing at time of writing).
At a glance
Hashimoto's antibody testing measures thyroid peroxidase (TPO) and thyroglobulin antibodies, the markers associated with Hashimoto's thyroiditis, the autoimmune process that is the most common cause of an underactive thyroid. It is designed for people whose TSH or Free T4 results are borderline, who have a family history of autoimmune thyroid conditions, or who want to understand whether autoimmune activity may be behind their symptoms. Panels pair antibody markers with TSH, Free T4, and Free T3 for full context.
Best suited for
- People with borderline or fluctuating TSH, Free T4, or Free T3 results who want antibody context before their next doctor visit
- Adults with a family history of Hashimoto's thyroiditis or other autoimmune conditions seeking a baseline antibody measurement
- Anyone with symptoms such as fatigue, weight gain, cold sensitivity, or thinning hair whose basic thyroid results have been inconclusive
- Women with heavy or irregular menstrual cycles, mood changes, or memory issues discussing possible thyroid involvement with their doctor
- People already tracking thyroid hormones who want to add autoimmune markers to their monitoring
What's included
Thyroid Peroxidase and Thyroglobulin Antibodies Test
TPO and TgAb autoimmune markers
TH-1 Hashimoto's Disease Panel
Free T3, Free T4, and TSH (3 tests, 3 biomarkers)
TH-2 Hashimoto's Disease Panel
13 tests, 76 biomarkers
TH-3 Hashimoto's Disease Panel
15 tests, 79 biomarkers, includes autoimmune markers
TH-4 Hashimoto's Disease Panel
17 tests, 81 biomarkers, the most comprehensive option
Thyroid Foundation Panel
13 tests, 23 biomarkers
Thyroid Foundation Panel Plus Thyroid Panel Add-On
15 tests, 78 biomarkers
TSH Test
T4 Free Test
T3 Free Test
T3 Reverse (rT3) Test
Key biomarker ranges
Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.
Commonly used reference ranges run roughly 0.4–4.0 µIU/mL; TSH moves inversely to thyroid activity, and time of day, illness, and biotin can skew results.
| Zone | Range |
|---|---|
| Low | 0–0.4 µIU/mL |
| Normal range | 0.4–4 µIU/mL |
| Mildly elevated | 4–6 µIU/mL |
| High | 6–10 µIU/mL |
Commonly used reference ranges run roughly 2.3–4.2 pg/mL; Free T3 is best interpreted alongside TSH and Free T4 rather than in isolation.
| Zone | Range |
|---|---|
| Low | 0–2.3 pg/mL |
| Normal range | 2.3–4.2 pg/mL |
| High | 4.2–6 pg/mL |
Commonly used reference ranges run roughly 0.8–1.8 ng/dL; Free T4 shows thyroid hormone supply, while TSH shows the pituitary’s demand signal.
| Zone | Range |
|---|---|
| Low | 0–0.8 ng/dL |
| Normal range | 0.8–1.8 ng/dL |
| High | 1.8–3 ng/dL |
The importance of testing
Autoimmune thyroid changes often progress quietly. Antibodies that target thyroid peroxidase, an enzyme essential for hormone production, and thyroglobulin can be present well before hormone levels drift out of range, which is why antibody testing adds a dimension that TSH alone cannot provide.
TPO and thyroglobulin antibodies are markers associated with Hashimoto's thyroiditis. Measuring them alongside TSH, Free T4, and Free T3 helps separate two different questions: how much hormone your thyroid is producing right now, and whether immune activity directed at the thyroid is present. Both pieces of information are useful when your doctor is interpreting borderline or fluctuating results.
The panels on this promotion range from the focused Thyroid Peroxidase and Thyroglobulin Antibodies Test to the comprehensive TH-3 and TH-4 Hashimoto's panels, which combine antibody markers with thyroid function, metabolic, and nutritional testing across as many as 17 tests and 81 biomarkers. That breadth makes it easier to establish a full baseline in a single blood draw.
Antibody results are not a medical conclusion, they are data points to review with your healthcare provider. Tracking them over time, together with your hormone levels and symptoms, gives your doctor a clearer picture for any decisions about monitoring or therapy.
Promo code
THHYPO20Save 20% with code THHYPO20, current promotion; confirm final pricing on the partner page.
Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.
Order NowFrequently asked questions
What does Hashimoto's antibody testing measure?
It measures thyroid peroxidase (TPO) and thyroglobulin antibodies, which target the enzyme and protein the thyroid uses to produce hormone and are markers associated with Hashimoto's thyroiditis. Most panels pair these antibody markers with TSH, Free T4, and Free T3 so hormone output and autoimmune activity can be viewed together. Results are data to review with your doctor, not a medical conclusion.
Why test thyroid antibodies if my TSH is normal?
Because antibody markers associated with autoimmune thyroid activity can be present before TSH or hormone levels move out of range. A normal TSH tells you about current hormone signaling, while TPO and thyroglobulin antibodies add information about whether immune activity directed at the thyroid is present. Discussing both with your doctor can clarify borderline or fluctuating results.
Which Hashimoto's panel should I choose?
The focused Thyroid Peroxidase and Thyroglobulin Antibodies Test covers the two core antibody markers, while the TH-3 and TH-4 Hashimoto's panels combine antibodies with thyroid function, metabolic, and nutritional markers across up to 17 tests and 81 biomarkers. If you only need hormone levels, the TH-1 panel measures Free T3, Free T4, and TSH. Your doctor can help match the depth of testing to your situation.
Can I order Hashimoto's antibody testing without a doctor's visit?
Yes, these tests are ordered directly online through the partner page, so no prior doctor's appointment is needed to purchase. You complete a blood draw at a local lab and receive results to review with your own healthcare provider. Any decisions about monitoring or therapy should be made with your doctor.
Is this testing available in every US state?
No, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout. Most other US states are served, and checkout will confirm availability in your area.
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