MetabolicMarkers

Educational content only, not medical advice. We are not a medical provider; review your results with a licensed physician. Details

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Hyperthyroidism & Graves' Disease Blood Tests: TSH, Free T3 & T4

Measure the thyroid hormones and autoimmune antibodies associated with an overactive thyroid, from a simple three-test snapshot to comprehensive 17-test panels.

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Individual thyroid tests from $17.56 and multi-test panels from $49.38 after the 20% discount (promotional pricing at time of writing).

At a glance

Hyperthyroidism and Graves' disease blood testing measures thyroid stimulating hormone (TSH), Free T3, and Free T4, and, in expanded panels, autoimmune antibodies such as thyroid stimulating immunoglobulin (TSI) and thyroid peroxidase antibodies, to screen for patterns associated with an overactive thyroid. These panels are for adults experiencing symptoms like unexplained weight loss, rapid heartbeat, anxiety, or heat sensitivity, and for anyone monitoring thyroid markers with their doctor. Panels range from a basic three-test check to comprehensive arrays covering 80-plus biomarkers.

Best suited for

  • Adults noticing symptoms often associated with an overactive thyroid, unexplained weight loss, rapid or irregular heartbeat, anxiety, tremors, increased perspiration, or heat sensitivity, who want concrete numbers to review with their doctor
  • Women tracking changes in menstrual cycles, energy, or weight, since thyroid conditions are more prevalent in women
  • People with a personal or family history of thyroid or autoimmune conditions who want periodic screening of TSH, Free T3, Free T4, and thyroid antibodies
  • Anyone already working with a clinician on a thyroid condition who wants convenient lab monitoring between appointments
  • Health-conscious self-trackers establishing a thyroid baseline before symptoms ever become a question

What's included

TH-1 Hyperthyroidism Panel

3 tests: TSH, Free T3, Free T4

TH-2 Hyperthyroidism Panel

13 tests, 76 biomarkers, adds broader health markers

TH-3 Hyperthyroidism Panel

15 tests, 79 biomarkers, adds metabolic, blood-health, and nutritional markers

TH-4 Hyperthyroidism Panel

17 tests, 81 biomarkers, includes autoimmune markers

TH-1 Graves' Disease Panel

3 tests: TSH, Free T3, Free T4

TH-2 Graves' Disease Panel

13 tests, 76 biomarkers

TH-3 Graves' Disease Panel

15 tests, 79 biomarkers, thyroid function plus autoimmune markers

TH-4 Graves' Disease Panel

17 tests, 81 biomarkers, the most comprehensive option

Thyroid Foundation Panel

13 tests, 23 biomarkers

Thyroid Foundation Panel Plus Thyroid Panel Add-On

15 tests, 78 biomarkers

Thyroid Add-On Panel

3 tests, 55 biomarkers

TSH Test

Thyroid stimulating hormone (thyrotropin)

T4 Free Test

Free thyroxine (FT4)

T3 Free Test

Free triiodothyronine (FT3)

T4 Total Test

Bound plus unbound thyroxine

T3 Total Test

Bound plus unbound triiodothyronine

T3 Reverse Test

Reverse T3 (rT3), an inactive form of T3

Thyroid Peroxidase and Thyroglobulin Antibodies Test

TPO and TgAb autoimmune markers

TSI Test

Thyroid stimulating immunoglobulin, a marker associated with Graves' disease

Deep-dive the key markers: TSH, Free T3, Free T4

Key biomarker ranges

Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.

TSH (µIU/mL)

Commonly used reference ranges run roughly 0.4–4.0 µIU/mL; TSH moves inversely to thyroid activity, and time of day, illness, and biotin can skew results.

TSH reference ranges (µIU/mL)
ZoneRange
Low00.4 µIU/mL
Normal range0.44 µIU/mL
Mildly elevated46 µIU/mL
High610 µIU/mL
Free T3 (pg/mL)

Commonly used reference ranges run roughly 2.3–4.2 pg/mL; Free T3 is best interpreted alongside TSH and Free T4 rather than in isolation.

Free T3 reference ranges (pg/mL)
ZoneRange
Low02.3 pg/mL
Normal range2.34.2 pg/mL
High4.26 pg/mL
Free T4 (ng/dL)

Commonly used reference ranges run roughly 0.8–1.8 ng/dL; Free T4 shows thyroid hormone supply, while TSH shows the pituitary’s demand signal.

Free T4 reference ranges (ng/dL)
ZoneRange
Low00.8 ng/dL
Normal range0.81.8 ng/dL
High1.83 ng/dL

The importance of testing

Your thyroid sets the pace for much of your metabolism, so when it produces too much hormone, the effects show up across the body, heart rate, weight, energy, mood, digestion, and body temperature. The core lab pattern to understand is the relationship between TSH and the free thyroid hormones: TSH is the pituitary's signal to the thyroid, so a suppressed TSH alongside elevated Free T4 or Free T3 is a pattern commonly associated with an overactive thyroid. Measuring all three together gives you and your doctor far more context than any single number.

Antibody testing adds another layer. Graves' disease, an autoimmune condition, is the most common cause of hyperthyroidism, and it leaves measurable fingerprints in the blood: thyroid stimulating immunoglobulin (TSI) and thyroid peroxidase and thyroglobulin antibodies (TPO and TgAb) are markers associated with autoimmune thyroid activity. If your hormone levels look off, antibody results are exactly the kind of data worth bringing to your doctor to discuss what may be driving the change.

Because an overactive thyroid influences so many systems, the larger panels in this collection (TH-2 through TH-4) pair thyroid hormones and antibodies with broader metabolic, blood-health, and nutritional markers, up to 81 biomarkers, so you can see the wider picture in one draw. That breadth is also useful for tracking: repeating the same panel over time shows whether your markers are trending toward, holding within, or moving away from reference ranges, which is valuable context whether you are establishing a baseline or following a care plan your clinician manages.

None of these tests replaces medical care, lab results are a starting point for a conversation, not a conclusion. Use them to arrive at your appointment with concrete numbers, flag anything out of range for your doctor to review, and follow changes between visits.

Promo code

THHYPER20

Save 20% with code THHYPER20, current promotion; confirm final pricing on the partner page.

Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.

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Frequently asked questions

What blood tests screen for hyperthyroidism?

The core blood tests for evaluating an overactive thyroid are TSH, Free T4, and Free T3. A suppressed TSH combined with elevated free thyroid hormone levels is a pattern associated with hyperthyroidism, and expanded panels add antibody, metabolic, and nutritional markers for a fuller picture. Whatever panel you choose, results are best reviewed with your doctor, who can interpret them in the context of your symptoms and history.

How is Graves' disease testing different from standard thyroid testing?

Graves' disease testing adds autoimmune antibody measurements, most notably thyroid stimulating immunoglobulin (TSI) plus thyroid peroxidase and thyroglobulin antibodies, on top of the standard TSH, Free T3, and Free T4. Elevated TSI is a marker associated with Graves' disease, the most common cause of hyperthyroidism, so antibody results give your doctor important context about whether an autoimmune process may be involved.

Can I order these thyroid tests without a doctor's visit?

Yes, these panels are sold through a direct-access lab testing partner, so you can order online, visit a local draw site for a blood sample, and receive your results without needing a referral first. Quick, reliable results are delivered directly to you, and any out-of-range values are worth bringing to your doctor to review.

Which hyperthyroidism panel should I choose?

A basic three-test panel (TSH, Free T3, Free T4) is a sensible starting point if you want an initial snapshot of thyroid function. The mid-tier and comprehensive panels (TH-2 through TH-4, with up to 81 biomarkers) add autoimmune antibodies plus metabolic, blood-health, and nutritional markers, useful if you want deeper context in a single draw or are tracking markers over time with your clinician.

How much does hyperthyroidism and Graves' disease testing cost?

With the current 20% promotion (code THHYPER20), individual thyroid tests start at $17.56 and multi-test panels start at $49.38, with the most comprehensive 17-test panels at $497.86. These are promotional prices at the time of writing, confirm final pricing on the partner page before ordering.

Is this testing available in every US state?

No, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout. If you live elsewhere in the US, you can typically order online and use a nearby draw location.