Current promotion
Hormone Imbalance Blood Tests: Fatigue, Mood & Cycle Changes
When symptoms are vague, numbers help, 12 hormone markers screened from a single blood draw.
Affiliate disclosure: we earn a commission when you purchase lab tests through links on this site, at no extra cost to you. Learn more
Women's Hormone Harmony Panel $238.40 with code (reg. $298); smaller HH-1 to HH-4 women's hormone panels from $87.88 (promotional pricing at time of writing).
At a glance
If you are dealing with persistent fatigue, mood swings, weight changes, or irregular cycles, hormone blood testing measures the markers most commonly associated with those symptoms. This 12-biomarker panel screens reproductive hormones (estradiol, progesterone, total and free testosterone, FSH, LH, prolactin), thyroid function (TSH, Free T3, Free T4), and adrenal markers (DHEA-S, AM cortisol) in a single draw. The result is objective data you can bring to your doctor, ordered online, with physician authorization included and most results back in 24 to 48 hours.
Best suited for
- Women with ongoing fatigue, brain fog, or mood changes that have not been explained
- Anyone with irregular, missing, or newly changed menstrual cycles who wants the relevant markers measured
- Women noticing unexplained weight changes, hair loss, or skin changes commonly associated with hormone shifts
- Those who want one broad screen across thyroid, adrenal, and reproductive markers before a doctor's appointment
- Anyone who prefers tracking lab values over time rather than guessing from symptoms alone
What's included
Estradiol (E2)
Progesterone
Total Testosterone
Free Testosterone
DHEA-Sulfate (DHEA-S)
Cortisol (AM)
Follicle Stimulating Hormone (FSH)
Luteinizing Hormone (LH)
Thyroid Stimulating Hormone (TSH)
Free T3
Free T4
Prolactin
Deep-dive the key markers: Estradiol, Total Testosterone, TSH, Free T3, Free T4
Key biomarker ranges
Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.
Adult female follicular-phase ranges shown; estradiol varies widely across the cycle and drops after menopause, so cycle timing is essential to interpretation.
| Zone | Range |
|---|---|
| Low | 0–30 pg/mL |
| Follicular range | 30–150 pg/mL |
| High | 150–250 pg/mL |
Adult male ranges shown; commonly used reference ranges run roughly 300–1,000 ng/dL, with morning draws the standard since levels peak early in the day.
| Zone | Range |
|---|---|
| Low | 0–300 ng/dL |
| Normal range | 300–1000 ng/dL |
| High | 1000–1200 ng/dL |
Commonly used reference ranges run roughly 0.4–4.0 µIU/mL; TSH moves inversely to thyroid activity, and time of day, illness, and biotin can skew results.
| Zone | Range |
|---|---|
| Low | 0–0.4 µIU/mL |
| Normal range | 0.4–4 µIU/mL |
| Mildly elevated | 4–6 µIU/mL |
| High | 6–10 µIU/mL |
The importance of testing
Symptoms like fatigue, brain fog, mood changes, and weight gain are nonspecific, each is associated with markers in more than one hormone system. Low thyroid hormone levels, disrupted cortisol patterns, and shifting reproductive hormones can all show up as the same lived experience. Testing one hormone at a time means guessing which system to check first; a broad panel screens all three at once.
Cycle-related symptoms follow the same logic. Irregular or missed periods are associated with several different markers, prolactin, the FSH-to-LH relationship, thyroid function, and androgens such as testosterone and DHEA-S among them. Measuring these together gives your clinician a much richer starting picture than any single test.
A panel like this is not intended to confirm anything on its own, and that is the point. It produces concrete values with reference ranges, flags results that fall outside them, and gives you and your doctor specific numbers to investigate, retest, and track over time instead of cycling through symptoms verbally at each visit.
The process is simple: order online, have your sample collected at a Quest location, and receive physician-reviewed results through a secure, HIPAA-compliant portal, most within 24 to 48 hours.
Promo code
HHW20Save 20% with code HHW20, current promotion; confirm final pricing on the partner page.
Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.
Order NowFrequently asked questions
Which hormones should be tested for fatigue and mood changes?
Fatigue and mood changes are most commonly associated with thyroid markers (TSH, Free T3, Free T4), the adrenal markers cortisol and DHEA-S, and reproductive hormones such as estradiol, progesterone, and testosterone. This panel measures all of those in one draw, so a single collection covers the systems your doctor is most likely to want to see.
Can this panel tell me why my periods are irregular?
It cannot provide a medical conclusion on its own, but it measures the markers most often reviewed when cycles are irregular, prolactin, FSH, LH, estradiol, progesterone, thyroid function, and androgens like testosterone and DHEA-S. Out-of-range results are flagged with reference ranges so you can review the pattern with your doctor and decide on next steps.
Do I need a doctor's visit to order this testing?
No, physician authorization is included with every order, so you can order online without a separate doctor's visit. Your blood is drawn at a Quest location, and results are physician-reviewed and delivered through a secure portal for you to share with your own provider.
Do I need to fast before this hormone test?
No, fasting is not required for this panel. An early-morning draw is still a reasonable choice for consistency, especially since the panel includes an AM cortisol measurement, which is timing-sensitive.
Can I order this test in any state?
Not quite, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout. In other states, collection is available nationwide through Quest, with most results in 24 to 48 hours.
Related lab test panels
Chronic Fatigue Blood Test Panels: Basic to Comprehensive
Four tiered lab panels that screen the hormonal, nutritional, and metabolic markers most often associated with persistent fatigue.
View panelThyroid Function Blood Test Panels: TSH, Free T4 & Free T3
From a basic TSH and T4 screen to a full antibody workup, thyroid panels for every level of detail.
View panelWomen's Hormone Blood Test Panels: Estradiol, FSH, LH & More
Four tiered blood panels that measure the hormones shaping your cycle, mood, energy, and metabolism.
View panel