MetabolicMarkers

Educational content only, not medical advice. We are not a medical provider; review your results with a licensed physician. Details

Current promotion

Thyroid Antibody Testing: TPO, Thyroglobulin, TSI & TRAb

See your immune markers and thyroid hormones together in one blood draw.

Affiliate disclosure: we earn a commission when you purchase lab tests through links on this site, at no extra cost to you. Learn more

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Panels from $36.76 with the 20% promotion; the antibody-inclusive Comprehensive panel is $271.16 (regularly $338.95), promotional pricing at time of writing.

At a glance

Thyroid antibody testing measures thyroid peroxidase (TPO) antibodies, thyroglobulin antibodies, thyroid-stimulating immunoglobulin (TSI), and TRAb, blood markers associated with autoimmune thyroid activity. The comprehensive panels on this page pair those antibody results with TSH, Free T4, and Free T3, so hormone function and immune markers appear side by side. This testing is designed for adults with thyroid-related symptoms, a family history of autoimmune conditions, or borderline hormone results who want a fuller picture to review with their doctor.

Best suited for

  • Adults with thyroid-related symptoms whose basic hormone results came back normal or borderline
  • People with a family history of autoimmune or thyroid conditions who want antibody markers checked
  • Anyone previously told they had elevated thyroid antibodies who wants to track those markers over time
  • Adults who want hormone levels and autoimmune markers measured together in a single blood draw

What's included

Thyroid Health - Comprehensive Lab Panel

10 tests including TPO and thyroglobulin antibodies, TSI, Reverse T3, and thyroxine-binding globulin

Thyroid Profile 11 (11 Tests)

10 tests, 12 biomarkers

Thyroid Foundation Panel

13 tests, 23 biomarkers

Thyroid Foundation Panel Plus Thyroid Panel Add-On

15 tests, 78 biomarkers

The Top 10 Thyroid Lab Tests

9 tests, 11 biomarkers

Thyroid Health - Basic Lab Panel

Hormone-only baseline: T3 Uptake, T4 Total, Free T4, and TSH

Thyroid Health - Basic Plus Lab Panel

Hormone-only screen adding T3 Total and Free T3

Deep-dive the key markers: TSH, Free T3, Free T4

Key biomarker ranges

Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.

TSH (µIU/mL)

Commonly used reference ranges run roughly 0.4–4.0 µIU/mL; TSH moves inversely to thyroid activity, and time of day, illness, and biotin can skew results.

TSH reference ranges (µIU/mL)
ZoneRange
Low00.4 µIU/mL
Normal range0.44 µIU/mL
Mildly elevated46 µIU/mL
High610 µIU/mL
Free T3 (pg/mL)

Commonly used reference ranges run roughly 2.3–4.2 pg/mL; Free T3 is best interpreted alongside TSH and Free T4 rather than in isolation.

Free T3 reference ranges (pg/mL)
ZoneRange
Low02.3 pg/mL
Normal range2.34.2 pg/mL
High4.26 pg/mL
Free T4 (ng/dL)

Commonly used reference ranges run roughly 0.8–1.8 ng/dL; Free T4 shows thyroid hormone supply, while TSH shows the pituitary’s demand signal.

Free T4 reference ranges (ng/dL)
ZoneRange
Low00.8 ng/dL
Normal range0.81.8 ng/dL
High1.83 ng/dL

The importance of testing

Standard thyroid screening measures hormones, TSH, T4, and T3, but hormone levels alone don't show whether the immune system is involved. Antibody tests add that dimension: thyroid peroxidase and thyroglobulin antibodies are markers associated with autoimmune thyroid conditions such as Hashimoto's thyroiditis, while TSI and TRAb are markers associated with Graves' disease.

Antibody results are often most informative when hormone values are borderline or fluctuating. Elevated antibodies alongside a normal TSH, for example, are a data point worth tracking over time and discussing with your doctor, because they describe immune activity that hormone tests by themselves can't capture.

The comprehensive panels here also include Reverse T3 and thyroxine-binding globulin, which add context on how thyroid hormone is metabolized and transported. Together, the hormone, binding-protein, and antibody results give your doctor a more complete dataset than a TSH-only screen.

As with any lab work, antibody results are information to review with a clinician, not a medical conclusion. Your doctor can interpret the pattern across markers in the context of your symptoms, history, and any medications.

Promo code

ULTATH

Save 20% with code ULTATH, current promotion; confirm final pricing on the partner page.

Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.

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Frequently asked questions

What do thyroid antibody tests measure?

They measure antibodies directed at thyroid components: thyroid peroxidase (TPO) antibodies, thyroglobulin antibodies, thyroid-stimulating immunoglobulin (TSI), and TRAb. TPO and thyroglobulin antibodies are markers associated with autoimmune conditions such as Hashimoto's thyroiditis, while TSI and TRAb are markers associated with Graves' disease.

Can my thyroid antibodies be high even if my TSH is normal?

Yes, antibody levels and hormone levels are separate measurements, and antibodies can be elevated while TSH, T4, and T3 remain in range. That combination is worth tracking over time and reviewing with your doctor, since it reflects immune activity that hormone tests alone don't capture.

Which panel includes thyroid antibody testing?

The Thyroid Health - Comprehensive Lab Panel includes TPO antibodies, thyroglobulin antibodies, and TSI alongside TSH, total and free T4 and T3, Reverse T3, and thyroxine-binding globulin. Hormone-only options like the Basic and Basic Plus panels are available if you only need a function screen.

Can I order thyroid antibody testing without a doctor's visit?

Yes, these panels are ordered directly online through the partner page, with the blood draw done at a local lab, so no doctor's appointment is required to purchase. Plan to review the results with your own doctor, who can interpret antibody patterns alongside your hormones and symptoms.

Is this testing available in every US state?

No. Direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout.