MetabolicMarkers

Educational content only, not medical advice. We are not a medical provider; review your results with a licensed physician. Details

Current promotion

Advanced Cardiovascular Testing: ApoB, Lp(a) & hs-CRP Panels

The risk markers a routine cholesterol test leaves out, measured in one blood draw.

Affiliate disclosure: we earn a commission when you purchase lab tests through links on this site, at no extra cost to you. Learn more

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Advanced panels from $112.76 with the 20% promotion; the full range spans $15.63–$408.76 promotional (list $22.95–$510.95, at time of writing).

At a glance

Advanced cardiovascular testing measures risk markers that a standard cholesterol panel does not report: Apolipoprotein B (a count-based measure of atherogenic particles), Lipoprotein (a) (a largely inherited marker associated with atherosclerosis risk), hs-CRP and homocysteine (inflammation markers), and metabolic measures like hemoglobin A1c and insulin. It is built for people whose basic lipid results look fine, or borderline, but who want a deeper, particle-level and inflammation-aware view to discuss with their doctor.

Best suited for

  • People whose standard cholesterol results are normal or borderline but who want particle-level detail like ApoB
  • Adults with a family history of early cardiovascular events who have never had Lp(a) measured
  • Anyone who wants inflammation markers (hs-CRP, homocysteine) tested alongside their lipids
  • Data-driven adults tracking how lifestyle or medication changes move advanced markers over time

What's included

Cardio IQ™ Max Lipid Panel

8 tests, 27 biomarkers, advanced lipoprotein analysis

Cardio IQ™ Max Lipid Panel + Fibrinogen Antigen

9 tests, 28 biomarkers, adds fibrinogen antigen

Heart Health - Advanced

13 tests, 32 biomarkers, lipids, inflammation markers, blood glucose, and more

Heart Health - Comprehensive

16 tests, 36 biomarkers, cholesterol, inflammation, clotting, blood sugar, and kidney function markers

Heart Health - Basic Plus

6 tests, 14 biomarkers, mid-tier option with inflammation and metabolic markers

Heart Health - Basic

3 tests, 11 biomarkers, entry-level option beyond a lipid panel

Lipid Panel Test

1 test, 6 biomarkers, standard cholesterol baseline for comparison

Deep-dive the key markers: Fasting Glucose, HbA1c, Fasting Insulin, ApoB, LDL-C, HDL-C, Triglycerides, Lp(a), hs-CRP, TSH, Vitamin D

Key biomarker ranges

Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.

Fasting Glucose (mg/dL)

Commonly used reference ranges place fasting glucose at 70–99 mg/dL; results vary with sleep, stress, and recent illness, and labs differ slightly.

Fasting Glucose reference ranges (mg/dL)
ZoneRange
Low5070 mg/dL
Optimal70100 mg/dL
Prediabetic range100126 mg/dL
Diabetic range126160 mg/dL
Hemoglobin A1c (%)

Commonly used reference ranges place HbA1c below 5.7%; conditions affecting red blood cells can skew results, so labs and clinicians interpret in context.

Hemoglobin A1c reference ranges (%)
ZoneRange
Optimal45.7 %
Prediabetic range5.76.5 %
Diabetic range6.510 %
Fasting Insulin (µIU/mL)

Commonly used reference ranges accept up to ~25 µIU/mL, but many clinicians view single-digit fasting insulin as the more informative target; assays vary by lab.

Fasting Insulin reference ranges (µIU/mL)
ZoneRange
Low02 µIU/mL
Optimal210 µIU/mL
Above optimal1025 µIU/mL
High2530 µIU/mL

The importance of testing

LDL cholesterol reports the amount of cholesterol carried in particles, but Apolipoprotein B counts the particles themselves, and particle number is a distinct marker associated with atherosclerosis risk. Measuring ApoB alongside ApoA1 shows the balance between atherogenic and protective lipoproteins, adding a dimension your standard panel does not capture.

Lipoprotein (a) is different again: it is largely determined by genetics, is not reflected in routine cholesterol results, and is typically worth measuring at least once. If your family history includes early cardiovascular events, an Lp(a) result gives you and your doctor a concrete data point rather than an open question.

Inflammation and metabolic markers round out the picture. hs-CRP tracks low-grade inflammation associated with cardiovascular risk, homocysteine is a marker associated with arterial stress, and glucose, hemoglobin A1c, and insulin show how blood sugar control and insulin resistance intersect with your lipid numbers. The largest panels add BNP, Cystatin C, Fibrinogen, Myeloperoxidase Antibody, Omega-3 and -6 fatty acids, Vitamin D, and TSH.

Because many of these markers respond to diet, training, and medication, while others, like Lp(a), stay relatively stable, retesting over time separates what you can move from what you simply need to know about, and gives your doctor a far richer dataset to work from.

Promo code

ULTA2191

Save 20% with code ULTA2191, current promotion; confirm final pricing on the partner page.

Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.

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Frequently asked questions

What does advanced cardiovascular testing measure that a regular cholesterol test doesn't?

Advanced panels add Apolipoprotein B and ApoA1 (lipoprotein particle balance), Lipoprotein (a), inflammation markers like hs-CRP and homocysteine, and metabolic measures such as hemoglobin A1c and insulin, none of which appear on a standard lipid panel. The largest tiers also include BNP, Cystatin C, Fibrinogen, Myeloperoxidase Antibody, Omega-3 and -6 fatty acids, Vitamin D, Sed Rate, and TSH.

Why measure ApoB if I already know my LDL cholesterol?

ApoB counts atherogenic lipoprotein particles directly, while LDL cholesterol measures the cholesterol those particles carry, and the two can diverge. ApoB is a marker associated with atherosclerosis risk that can add context when LDL alone looks unremarkable; it is a useful result to review with your doctor.

Is Lp(a) worth testing more than once?

Lp(a) is largely genetically determined and stays relatively stable, so a single measurement is often informative for years. Many people test it once to establish their level, then focus repeat testing on markers that respond to lifestyle and therapy, such as ApoB, hs-CRP, and A1c.

Can I order advanced cardiovascular tests without a doctor's referral?

Yes, these panels can be ordered directly online without a doctor's visit or referral. After a blood draw at a partner lab location, you receive results you can review yourself and bring to your healthcare provider.

Is this testing available in all US states?

No, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout. Residents of other states can generally order online and use a local draw site.